The trust-inducing property of oxytocin might help those with social anxiety and depression,[29] anxiety, fear, and social dysfunctions, such as generalized anxiety disorder, posttraumatic stress disorder, and social anxiety disorder, as well as autism and schizophrenia, among others.[30] They also show improved recognition for positive social cues over threatening social cues [31][32] and improved recognition of fear.[33]

Autism: Oxytocin may play a role in autism and may be an effective treatment for autism‚s repetitive and affiliative behaviors.[34] Oxytocin treatments also resulted in an increased retention of affective speech in adults with autism.[35] Two related studies in adults, in 2003 and 2007, found oxytocin decreased repetitive behaviors and improved interpretation of emotions. More recently, intranasal administration of oxytocin was found to increase emotion recognition in children as young as 12 who are diagnosed with autism spectrum disorders.[36] After treatment with inhaled oxytocin, autistic patients exhibit more appropriate social behavior.[37] Early oxytocin treatment can perhaps change very early the impaired social development of autistic patients once diagnosed.[38] While this research suggests some promise, further clinical trials of oxytocin are required to demonstrate potential benefit and side effects in the treatment of autism. As such, researchers do not recommend use of oxytocin as a treatment for autism outside of clinical trials.[39]